Beginning in the 1790s, the American Philosophical Society began to accumulate vocabularies and texts written in Native American languages, guided by Thomas Jefferson's idea of using comparative linguistics to reconstruct the histories of Indian peoples and discern their origins. The American Indian Vocabularies Collection was initially assembled by the Historical and Literary Committee of the APS for publication in 1816. They include information on seventeen North American languages and one each from the Caribbean and Central America, collected between 1784 and 1828. A number of individuals were invovled in recording the vocabularies, including Benjamin Hawkins, William Thornton, David Campbell, Daniel Smith, Constantine Volney, Constantine Rafinesque, William Vans Murray, John Heckewelder, Martin Duralde, Campanius Holm, and Jefferson himself. Most followed the standardized word set established by Jefferson.

Trained as an anthropologist at Berkeley under A.L. Kroeber and Robert Lowie, Carl Voegelin spent the majority of his career as a structural linguist specializing in Algonquian languages, including Delaware, Potawatomi, Fox, Menominee, and Shawnee, and on the Seneca, Ojibwa (Chippewa), and Blackfoot (Siksika). His most significant contributions came through his studies of Delaware, Shawnee, and Hopi, but he is also credited with reviving the International Journal of American Linguistics after the death of its founder, Franz Boas, and with nurturing the program in anthropology at Indiana University, where he was on faculty from 1941 until his retirement in 1976. The Voegelin collection contains field notes, lexical files, notebooks, papers, correspondence, and other materials relating to Voegelin's work on Native American languages. The bulk of the collection concerns Delaware and Shawnee, but there is significant material for Blackfoot, Menominee, Ojibwa and Potawatomi, Seneca, and Penobscot. Notes on Turkish, kept during the Second World War, are also present. Among other important series in the collection are Voegelin's correspondence and notes concerning two of his major projects: the translation and interpretation of the Walam Olam and his study of Shawnee law. Correspondents include Leonard Bloomfield, Eli Lilly, and Morris Swadesh. A portion of the collection is indexed in Kendall (1982).